DeCS Server - List Exact Term

Search on:	MANNOSE-BINDING PROTEIN-ASSOCIATED SERINE PROTEASES
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DeCS

Descriptor English:

Mannose-Binding Protein-Associated Serine Proteases

Descriptor Spanish:

Serina Proteasas Asociadas a la Proteína de Unión a la Manosa

Descriptor Portuguese:

Serina Proteases Associadas a Proteína de Ligação a Manose

Tree Number:

Definition English:

Serum serine proteases which participate in COMPLEMENT ACTIVATION. They are activated when complexed with the MANNOSE-BINDING LECTIN, therefore also known as Mannose-binding protein-Associated Serine Proteases (MASPs). They cleave COMPLEMENT C4 and COMPLEMENT C2 to form C4b2a, the CLASSICAL PATHWAY C3 CONVERTASE.

Indexing Annotation English:

see SCR for organism-specific terms

Pharmacological Action:

History Note English:

2006 (1994)

Allowable Qualifiers English:

Record Number:

50582

Unique Identifier:

D050606

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